The Glucocorticoid Toxicity Index (GTI) was developed through an expert consensus approach using multi-criteria decision analysis. The 20 medical experts who participated in the development of the GTI are international authorities in their respective subspecialties, representing rheumatology, pulmonary medicine, nephrology, neurology, psychiatry, dermatology, maternal-fetal medicine, and infectious disease.
Enter a new era of steroid-sparing research, 70 years after steroids were first introduced
First clinical use of glucocorticoids
23 days later…
First report of toxicity described
The first and only glucocorticoid toxicity index (GTI) is introduced - weighted and standardized to measure steroid safety
The GTI was created by experts in several sub-specialities and is based on data-driven, peer-reviewed research.
February 2021: Avacopan for the Treatment of ANCA-Associated Vasculitis
January 2021: The Role of Quantification of Glucocorticoid-associated Toxicity in Severe Asthma
January 2021: The Vexed Problem of Corticosteroid Toxicity in Asthma: Time for Standardized Assessment
2016: Development of a Glucocorticoid Toxicity Index (GTI 1.0) Using Multicriteria Decision Analysis